Effects of Nitric Oxide on the Body
One of the effects of nitric oxide on the body is that it increases muscle growth through being a vasodilator, and when taken prior to and after workouts, it enables muscles to receive more blood and therefore, more oxygen and nutrients. This is critical to maximal muscle exertion during training and recovery afterward.
There are several other mechanisms by which nitric oxide has been demonstrated to affect the biology of living cells. These include oxidation of iron containing proteins such as ribonucleotide reductase and aconitase, activation of the soluble guanylate cyclase, ADP ribosylation of proteins, protein sulphhydryl group nitrosylation, and iron regulatory factor activation. NO has been demonstrated to activate NF-κB in peripheral blood mononuclear cells, an important transcription factor in iNOS gene expression in response to inflammation
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